I always like a bit of visual detective work. This is especially true of something so coordinated and modified as a TV commercial. Typically nearly everything is controlled in some fashion. With this obviously be an outdoor urban shot there are some aspects that even they could not control and in them are clues to the location of the shot. Consider these three aspects:
First, just a simple internet search reveals the company who produced the commercial. A bit more digging produced all the key company personnel involved with the actual filming and creation of the spot. From that there are some logical locations to consider.
The advertising company is based in Chicago, just like the beer company. However, the actual film crew was from a sub-contractor based on the west coast US. The company providing the actors also has offices in the west and a few other places.
Second, just looking at the scene also provides some clues. The architecture is generic urban however it is not very modern nor does it have the density associated with a large city core. Also, there are few distinct regional ques such as style, materials used or many telltale structures in the background that would tell of location. This is not arbitrary as the commercial would work better if this could be "anytown".
Third, just focusing on specific items that "accidentally" could show location and that probably were not inserted deliberately by the film crew include the following; Street sign at appears just after the Irish dancers, the car license plates parked in the background just as he enters the "bar" and the office tower visible in the background briefly just after that. Oh, and the spot was shot in 2012.
If you take all these elements and with a bit more internet searching one can make a very good assumption as to where it is set, and it is not Chicago.
I love how the bushes slide in from the right slightly just after he crosses the street - gotta love mobile plant props.