If you're keeping this to sit-com episodes with boobcentric plots or sub-plots, there's a very early "Just Shoot Me," in which Nina walks around with a large temporary set (not a new idea), and Maya tries to tell her of the dangers of implants. Nina angrily says that just because Maya has the biggest breasts in the office she doesn't want anyone bigger, to which our heroine replies something like, "Curses! You've seen through my plan to conquer the world with my breasts!" Of course every episode of JSM was boobcentric, as far as I'm concerned, but this was before the San Giacomo twins were quite the size they became and the focus of many good gags. And, ironically, before she DID conquer the world - or the part in which I live - with her splendid toys.